(Miura lab members in bold)

Pubmed publications

Current Preprints:

Gruner, H.N., Bae, B., Lynch, M., Oliver, D., So, K., Mastick, G.S., Yan, W., Miura, P. Precise removal of Calm1 long 3′ UTR isoform by CRISPR-Cas9 genome editing impairs dorsal root ganglion development in mice.


Zhang, Z., So, K., Peterson, R., Bauer, M., Ng, H., Zhang, Y., Kim, J.H., Kidd, T., Miura, P. Elav-mediated exon skipping and alternative polyadenylation of the Dscam1 gene are required for axon outgrowth. Cell Reports. 27, 3808–3817, 2019


Knupp, D., and Miura, P. CircRNA accumulation: A new hallmark of aging? Mechanisms of Ageing and Development. 67:108-119, 2018.

Singh, M., Miura, P., and Renden, R. Age-related defects in short-term plasticity are reversed by acetyl-L-carnitine at the mouse calyx of Held. Neurobiology of Aging. 67:108-119,  2018.

Cooper D.A., Cortés-López M., and Miura, P. Genome-Wide circRNA Profiling from RNA-seq Data. Methods in Molecular Biology. 1724:27-41, 2018.

Cortés-López, M., Gruner, M., Cooper, D.A., Gruner, H.N., Voda, A., van der Linden, A., and Miura, P. Global accumulation of circRNAs during aging in Caenorhabditis elegans. BMC Genomics. 19:8, 2018.


Hall, H., Medina, P., Cooper, D.A., Escobedo, S.E., Rounds, J., Brennan, K.J., Vincent, C., Miura, P., Doerge, R., and Weake, V.M. Transcriptome profiling of aging Drosophila photoreceptors reveals gene expression trends that correlate with visual senescenceBMC Genomics. 18:894, 2017.

Sanfilippo P., Miura P., Lai EC. Genome-wide profiling of the 3' ends of polyadenylated RNAs. Methods. pii: S1046-2023(17)30137-8. 2017.

Liu W., Klose A., Forman S., Paris N.D., Wei-LaPierre L., Cortés-Lopéz M., Tan A., Flaherty M., Miura P., Dirksen R.T., Chakkalakal J.V.. Loss of adult skeletal muscle stem cells drives age-related neuromuscular junction degeneration. Elife. Jun 6;6 pii: e26464, 2017.


Gruner, H., Cortés-López, M., Cooper, D.A., Bauer, M., and Miura, P. CircRNA accumulation in the aging mouse brain. Scientific Reports. 6:38907, 2016.

Cortés-López, M., and Miura, P. Emerging functions of circular RNAs. Yale Journal of Biology and Medicine, 89:527-537, 2016. 


Shenker, S., Miura, P., Sanfilippo, P and Lai, E.C. IsoSCM: Improved and alternative UTR annotation using multiple change-point inference. RNA. 21(1):14-27, 2015.


Westholm, J.O, Miura, P., Olson, S., Shenker, S., Joseph, B., Sanfilippo, P., Celniker, S.E., Graveley, B.J., and Lai, E.C. Genomewide analysis of Drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation.  Cell Reports, 9(5):1966-1980, 2014.

Miura, P., Shenker, S., Sanfilippo P, and Lai E.C. Alternative polyadenylation in the nervous system: to what lengths will 3' UTR extensions take us? Bioessays. 36(8):766-777, 2014.

Amirouche, A., Tadesse, H., Miura, P., Belanger G., Lunde, J., Côté, J., Jasmin, B.J. Converging Pathways Involving MicroRNA-206 and the RNA-Binding Protein KSRP Control Post-transcriptionally Utrophin A Expression in Skeletal Muscle. Nucleic Acids Research. 42(6):3982-3997, 2014.


Miura, P*., Shenker, S*., Andreu-Agullo, C., Westholm, J.O., and Lai, E.C. Widespread and extensive lengthening of 3' UTRs in the mammalian brain. Genome Research. 23(5):812-825, 2013. *, co-first authors

Smibert, P*., Miura, P*, Westholm, J.O., Shenker, S., May, G., Duff, M.O., Zhang, D., Eads, B.D., Carlson, J., Brown B.,Eisman, R.C., Andrews, J., Kaufman, C., Cherbas, P., Celniker, S.E., Graveley, B.J., and Lai, E.C. Global patterns of tissue-specific alternative polyadenylation in Drosophila. Cell Reports. 1(3):277-289, 2012.*, co-first authors

Corinaldi J, Nasrallah R, Clark J, Paris G, Miura P., Jasmin BJ, Hébert RL. Troglitazone induces extracellular matrix and cytoskeleton remodeling in mouse collecting duct cells. J Biomed Biotechnol. 2012:507057, 2012.

 Miura, P., Clow, C., Amirouche, A., Jasmin B.J. MicroRNA-206 Regulates BDNF Expression During Myogenic Differentiation. J Neurochem. 120(2):230-238, 2012.

Ljubicic V., Miura P., Burt M., Boudreault L., Khogali S., Lunde J.A., Renaud J.M., Jasmin B.J. Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle. Hum Mol Genet. 20(17):3478-3493, 2011.

Nasrallah, R., Clark, J., Corinaldi J., Paris, G., Miura, P., Jasmin, B.J., Hébert, R.L. Thiazolidinediones alter growth and epithelial cell integrity, independent of PPARγ and MAPK activation, in mouse M1 Cortical Collecting Duct Cells. Am J Physiol Renal Physiol. 298: F1105–F1112, 2010.

Miura, P.*, Coriati, A. *, Bélanger, G., Lee, J., Holcik, M., Kothary, R., Jasmin, B.J. The utrophin A 5’UTR drives cap-independent translation exclusively in skeletal muscles of transgenic mice and interacts with eEF1A2. Hum Mol Genet. 19(7):1211-1220, 2010. *, co-first authors

Miura, P., Chakkalakal, J.V., Boudreault, L., Bélanger, G., Hébert, R.L., Renaud, J.M., Jasmin, B.J. Pharmacological activation of PPARβ/δ stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice. Hum Mol Genet. 18(23):4640-4649, 2009.

Miura, P., Andrews, M., Holcik, M., Jasmin, B.J.  IRES-Mediated Translation of Utrophin A is Enhanced by Glucocorticoid Treatment in Skeletal Muscle Cells.  PLoS ONE. 3(6):e2309, 2008.

Chakkalakal, J.V., Miura, P., Bélanger G., Michel, R.N., Jasmin, B.J.  Modulation of Utrophin A mRNA stability in fast versus slow muscles via an AU-rich Element and Calcineurin Signaling. Nucleic Acids Res. 36:826-38, 2008.

Miura P., and Jasmin B.J. Utrophin upregulation for treating Duchenne or Becker muscular dystrophy: How close are we?  Trends Mol Med. 12:122-9, 2006.

Miura, P., Thompson, J., Chakkalakal, J.V., Holcik, M., Jasmin, B.J. The Utrophin A 5’UTR Confers IRES-Mediated Translational Control During Regeneration of Skeletal Muscle Fibers. J Biol Chem. 280, 32997-33005, 2005

Stocksley, M.A., Chakkalakal, J.V., Bradford, A., Miura, P., De Repentigny, Y., Kothary, R., Jasmin, B.J. A 1.3 kb promoter fragment confers spatial and temporal expression of utrophin A mRNA in mouse skeletal muscle fibers. Neuromuscul Disord. 15, 437-449, 2005.

Vaughan, P.S., Miura, P., Henderson, M., Byrne, B., and Vaughan, K.T. A role for regulated binding of p150(Glued) to microtubule plus ends in organelle transport. J Cell Biol. 158, 305-319, 2002.