Check out our latest pre-print: Precise removal of Calm1 long 3′ UTR isoform by CRISPR-Cas9 genome editing impairs dorsal root ganglion development in mice. https://www.biorxiv.org/content/10.1101/553990v1
The Miura lab studies two types of RNAs- extended 3´ UTR isoforms and circRNAs. Thousands of these RNAs exist in the brains of many organisms, including humans. One focus of the group is to uncover functions for such transcripts in the nervous system. The group uses mouse and Drosophila as model organisms, and employs high-throughput sequencing and CRISPR genome editing in our research.
Our work featured in a six-part story on Neuroscience research at UNR: